A novel ATM/TP53/p21-mediated checkpoint only activated by chronic γ-irradiation.

A novel ATM/TP53/p21-mediated checkpoint only activated by chronic γ-irradiation.

Different levels or types of DNA damage activate distinct signaling pathways that elicit various cellular responses, including cell-cycle arrest, DNA repair, senescence, and apoptosis. Whereas a range of DNA-damage responses have been characterized, mechanisms underlying subsequent cell-fate decisio...

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Bibliographic Details
Main Authors: Lili Cao, Hidehiko Kawai, Megumi Sasatani, Daisuke Iizuka, Yuji Masuda, Toshiya Inaba, Keiji Suzuki, Akira Ootsuyama, Toshiyuki Umata, Kenji Kamiya, Fumio Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25093836/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25093836/pdf/?tool=EBI

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