A novel injectable borate bioactive glass cement as an antibiotic delivery vehicle for treating osteomyelitis.

BACKGROUND: A novel injectable cement composed of chitosan-bonded borate bioactive glass (BG) particles was evaluated as a carrier for local delivery of vancomycin in the treatment of osteomyelitis in a rabbit tibial model. MATERIALS AND METHODS: The setting time, injectability, and compressive stre...

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Bibliographic Details
Main Authors: Hao Ding, Cun-Ju Zhao, Xu Cui, Yi-Fei Gu, Wei-Tao Jia, Mohamed N Rahaman, Yang Wang, Wen-Hai Huang, Chang-Qing Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3888432?pdf=render