Expression, Functional Characterization, and Preliminary Crystallization of the Cochaperone Prefoldin from the Thermophilic Fungus Chaetomium thermophilum

Expression, Functional Characterization, and Preliminary Crystallization of the Cochaperone Prefoldin from the Thermophilic Fungus Chaetomium thermophilum

Prefoldin is a hexameric molecular chaperone found in the cytosol of archaea and eukaryotes. Its hexameric complex is built from two related classes of subunits, and has the appearance of a jellyfish: Its body consists of a double β-barrel assembly with six long tentacle-like coiled coils p...

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Bibliographic Details
Main Authors: Kento Morita, Yohei Y. Yamamoto, Ayaka Hori, Tomohiro Obata, Yuko Uno, Kyosuke Shinohara, Keiichi Noguchi, Kentaro Noi, Teru Ogura, Kentaro Ishii, Koichi Kato, Mahito Kikumoto, Rocio Arranz, Jose M. Valpuesta, Masafumi Yohda
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
chaperone
chaperonin
Chaetomium thermophilum
proteostasis
interaction
folding
Online Access:http://www.mdpi.com/1422-0067/19/8/2452

Internet

http://www.mdpi.com/1422-0067/19/8/2452

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