Regulation of GVBD in mouse oocytes by miR-125a-3p and Fyn kinase through modulation of actin filaments

Abstract Meiotically arrested oocytes are characterized by the presence of the nuclear structure known as germinal-vesicle (GV), the breakdown of which (GVBD) is associated with resumption of meiosis. Fyn is a pivotal factor in resumption of the first meiotic division; its inhibition markedly decrea...

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Bibliographic Details
Main Authors: Hadas Grossman, Efrat Har-Paz, Natalie Gindi, Mattan Levi, Irit Miller, Nava Nevo, Dalia Galiani, Nava Dekel, Ruth Shalgi
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02071-x