Phage Display-based Strategies for Cloning and Optimization of Monoclonal Antibodies Directed against Human Pathogens

Phage Display-based Strategies for Cloning and Optimization of Monoclonal Antibodies Directed against Human Pathogens

In the last two decades, several phage display-selected monoclonal antibodies (mAbs) have been described in the literature and a few of them have managed to reach the clinics. Among these, the anti-respiratory syncytial virus (RSV) Palivizumab, a phage-display optimized mAb, is the only marketed mAb...

Full description

Bibliographic Details
Main Authors: Roberto Burioni, Matteo Castelli, Massimo Clementi, Laura Solforosi, Nicasio Mancini, Nicola Clementi
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:International Journal of Molecular Sciences
Subjects:
phage display
library construction
monoclonal antibodies
biopanning
hypervariable pathogens
Online Access:http://www.mdpi.com/1422-0067/13/7/8273

Internet

http://www.mdpi.com/1422-0067/13/7/8273

Similar Items