Increased percentages of T helper cells producing IL-17 and monocytes expressing markers of alternative activation in patients with sepsis.

BACKGROUND: A shift from Th1 to Th2 as well as an increase in Treg CD4+T cell subsets has been reported in septic patients (SP). Furthermore, these patients display modulation of monocyte function, with reduced production of pro-inflammatory cytokines upon LPS stimulus, which resembles the phenotype...

Full description

Bibliographic Details
Main Authors: Milena Karina Colo Brunialti, Michelle Carolina Santos, Otelo Rigato, Flavia Ribeiro Machado, Eliezer Silva, Reinaldo Salomao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3365066?pdf=render