Inhibition of Androgen-Independent Prostate Cancer by Estrogenic Compounds Is Associated with Increased Expression of Immune-Related Genes

Inhibition of Androgen-Independent Prostate Cancer by Estrogenic Compounds Is Associated with Increased Expression of Immune-Related Genes

The clinical utility of estrogens for treating prostate cancer (CaP) was established in the 1940s by Huggins. The classic model of the anti-CaP activity of estrogens postulates an indirect mechanism involving the suppression of androgen production. However, clinical, preclinical studies have shown...

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Bibliographic Details
Main Authors: Ilsa M. Coleman, Jeffrey A. Kiefer, Lisha G. Brown, Tiffany E. Pitts, Peter S. Nelson, Kristen D. Brubaker, Robert L. Vessella, Eva Corey
Format: Article
Language:English
Published: Elsevier 2006-10-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Prostate cancer
estrogen
estradiol
androgen independence
interferon-regulated genes
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558606800904

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http://www.sciencedirect.com/science/article/pii/S1476558606800904

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