Long Noncoding RNA ANRIL: Lnc-ing Genetic Variation at the Chromosome 9p21 Locus to Molecular Mechanisms of Atherosclerosis

Long Noncoding RNA ANRIL: Lnc-ing Genetic Variation at the Chromosome 9p21 Locus to Molecular Mechanisms of Atherosclerosis

Ever since the first genome-wide association studies (GWAS) on coronary artery disease (CAD), the Chr9p21 risk locus has emerged as a top signal in GWAS of atherosclerotic cardiovascular disease, including stroke and peripheral artery disease. The CAD risk SNPs on Chr9p21 lie within a stretch of 58...

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Bibliographic Details
Main Authors: Lesca M. Holdt, Daniel Teupser
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
lncRNA (long non-coding RNA)
circRNA
GWAS (genome-wide association study)
eQTL analysis
transcription
splicing
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2018.00145/full

Internet

https://www.frontiersin.org/article/10.3389/fcvm.2018.00145/full

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