Abnormal Circadian Modification of Aδ-Fiber Pathway Excitability in Idiopathic Restless Legs Syndrome

Restless legs syndrome (RLS) is characterized by unpleasant sensations generally localized to legs, associated with an urge to move. A likely pathogenetic mechanism is a central dopaminergic dysfunction. The exact role of pain system is unclear. The purpose of the study was to investigate the nocice...

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Bibliographic Details
Main Authors: Catello Vollono, Giacomo Della Marca, Elisa Testani, Anna Losurdo, Daniela Virdis, Diana Ferraro, Valerio Brunetti, Paolo M. Rossini, Domenica Le Pera, Salvatore Mazza, Massimiliano Valeriani
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2019/5408732