The prevalence and phenotype of activated microglia/macrophages within the spinal cord of the hyperostotic mouse (twy/twy) changes in response to chronic progressive spinal cord compression: implications for human cervical compressive myelopathy.

The prevalence and phenotype of activated microglia/macrophages within the spinal cord of the hyperostotic mouse (twy/twy) changes in response to chronic progressive spinal cord compression: implications for human cervical compressive myelopathy.

BACKGROUND: Cervical compressive myelopathy, e.g. due to spondylosis or ossification of the posterior longitudinal ligament is a common cause of spinal cord dysfunction. Although human pathological studies have reported neuronal loss and demyelination in the chronically compressed spinal cord, littl...

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Bibliographic Details
Main Authors: Takayuki Hirai, Kenzo Uchida, Hideaki Nakajima, Alexander Rodriguez Guerrero, Naoto Takeura, Shuji Watanabe, Daisuke Sugita, Ai Yoshida, William E B Johnson, Hisatoshi Baba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3663759?pdf=render

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http://europepmc.org/articles/PMC3663759?pdf=render

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