Distinct cytokine profiles of circulating mononuclear cells stimulated with Staphylococcus aureus enterotoxin A in vitro during early and late episodes of chronic osteomyelitis

Distinct cytokine profiles of circulating mononuclear cells stimulated with Staphylococcus aureus enterotoxin A in vitro during early and late episodes of chronic osteomyelitis

We investigated the cytokine profile of peripheral mononuclear cells from chronic osteomyelitis (OST) patients following in vitro stimulation with staphylococcal enterotoxin A (SEA). We demonstrate that stimulation with SEA induced prominent lymphocyte proliferation and high levels of tumour necrosi...

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Bibliographic Details
Main Authors: Gabriella Freitas Ferreira, Cícero Moraes, Alda Maria Soares da Silveira, Rodrigo Correa-Oliveira, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho, Elizabeth Castro Moreno, Luiz Simeão do Carmo, Lucia Alves de Oliveira Fraga, Luiz Cosme Cotta Malaquias
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2012-05-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Staphylococcus aureus
enterotoxin A
chronic osteomyelitis
cytokines
IL-6
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000300009&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000300009&lng=en&tlng=en

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