Characterization of population-based variation and putative functional elements for the multiple-cancer susceptibility loci at 5p15.33 [v1; ref status: indexed, http://f1000r.es/49o]

Background: TERT encodes the telomerase reverse transcriptase, which is responsible for maintaining telomere ends by addition of (TTAGGG)n nucleotide repeats at the telomere.  Recent genome-wide association studies have found common genetic variants at the TERT-CLPTM1L locus (5p15.33) associated wit...

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Bibliographic Details
Main Authors: Lisa Mirabello, Charles C. Chung, Meredith Yeager, Sharon A Savage
Format: Article
Language:English
Published: F1000 Research Ltd 2014-10-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/3-231/v1