Influenza A Strain-Dependent Pathogenesis in Fatal H1N1 and H5N1 Subtype Infections of Mice

Influenza A Strain-Dependent Pathogenesis in Fatal H1N1 and H5N1 Subtype Infections of Mice

To determine if fatal infections caused by different highly virulent influenza A viruses share the same pathogenesis, we compared 2 different influenza A virus subtypes, H1N1 and H5N1. The subtypes, which had shown no pathogenicity in laboratory mice, were forced to evolve by serial passaging. Altho...

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Bibliographic Details
Main Authors: Mutien-Marie Garigliany, Adélite Habyarimana, Bénédicte Lambrecht, Els Van de Paar, Anne Cornet, Thierry van den Berg, Daniel Desmecht
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2010-04-01
Series:Emerging Infectious Diseases
Subjects:
Influenza
viruses
lung
acute respiratory distress syndrome
ARDS
research
Online Access:https://wwwnc.cdc.gov/eid/article/16/4/09-1061_article

Internet

https://wwwnc.cdc.gov/eid/article/16/4/09-1061_article

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