A Study of Cecal Ligation and Puncture-Induced Sepsis in Tissue-Specific Tumor Necrosis Factor Receptor 1-Deficient Mice

A Study of Cecal Ligation and Puncture-Induced Sepsis in Tissue-Specific Tumor Necrosis Factor Receptor 1-Deficient Mice

Sepsis is a complex syndrome resulting from a dysregulated immune response to an infection. Due to the high prevalence, morbidity, and mortality, there is a lot of interest in understanding pathways that play a role in sepsis, with a focus on the immune system. Tumor necrosis factor (TNF) is a pleio...

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Bibliographic Details
Main Authors: Jolien Vandewalle, Sophie Steeland, Sara Van Ryckeghem, Melanie Eggermont, Elien Van Wonterghem, Roosmarijn E. Vandenbroucke, Claude Libert
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
sepsis
inflammation
TNF
TNFR1
cecal ligation and puncture
lipopolysaccharide
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02574/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02574/full

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