Promising Antidiabetic and Antimicrobial Agents Based on Fused Pyrimidine Derivatives: Molecular Modeling and Biological Evaluation with Histopathological Effect

Promising Antidiabetic and Antimicrobial Agents Based on Fused Pyrimidine Derivatives: Molecular Modeling and Biological Evaluation with Histopathological Effect

Diabetes is the most common metabolic disorder in both developing and non-developing countries, and a well-recognized global health problem. The WHO anticipates an increase in cases from 171 million in 2000 to 366 million by 2030. In the present study, we focus on the preparation of pyrimidine deriv...

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Bibliographic Details
Main Authors: Fatma Bassyouni, Mohammad Tarek, Abeer Salama, Bassant Ibrahim, Sawsan Salah El Dine, Nemat Yassin, Amina Hassanein, Maysa Moharam, Mohamed Abdel-Rehim
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
molecular modeling
pyrimidine derivatives
antidiabetic activity
antimicrobial activity
histopathological study
Online Access:https://www.mdpi.com/1420-3049/26/8/2370

Internet

https://www.mdpi.com/1420-3049/26/8/2370

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