Metformin Ameliorates Testicular Function and Spermatogenesis in Male Mice with High-Fat and High-Cholesterol Diet-Induced Obesity

Metformin Ameliorates Testicular Function and Spermatogenesis in Male Mice with High-Fat and High-Cholesterol Diet-Induced Obesity

The aim of this study was to investigate the effects of metformin supplementation on metabolic dysfunction, testicular antioxidant capacity, apoptosis, inflammation and spermatogenesis in male mice with high-fat and high-cholesterol diet-induced obesity. Forty male C57BL/6 mice were fed a normal die...

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Bibliographic Details
Main Authors: Chin-Yu Liu, Ting-Chia Chang, Shyh-Hsiang Lin, Sheng-Tang Wu, Tai-Lung Cha, Chih-Wei Tsao
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Nutrients
Subjects:
high-fat and high-cholesterol diet
obesity
male infertility
metformin
spermatogenesis
Online Access:https://www.mdpi.com/2072-6643/12/7/1932

Internet

https://www.mdpi.com/2072-6643/12/7/1932

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