α-Mangostin Enhances Betulinic Acid Cytotoxicity and Inhibits Cisplatin Cytotoxicity on HCT 116 Colorectal Carcinoma Cells

α-Mangostin Enhances Betulinic Acid Cytotoxicity and Inhibits Cisplatin Cytotoxicity on HCT 116 Colorectal Carcinoma Cells

Despite the progress in colon cancer treatment, relapse is still a major obstacle. Hence, new drugs or drug combinations are required in the battle against colon cancer. α-Mangostin and betulinic acid (BA) are cytotoxic compounds that work by inducing the mitochondrial apoptosis pathway, and cisplat...

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Bibliographic Details
Main Authors: Amin Malik Shah Abdul Majid, Zhari Ismail, Khalid M. Abu-Salah, Abdalrahim F. A. Aisha
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Molecules
Subjects:
α-mangostin
betulinic acid
cisplatin
apoptosis
cytotoxicity enhancement
cytoprotection effects
Online Access:http://www.mdpi.com/1420-3049/17/3/2939/

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http://www.mdpi.com/1420-3049/17/3/2939/

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