Metagenomic Analysis of Serum Microbe-Derived Extracellular Vesicles and Diagnostic Models to Differentiate Ovarian Cancer and Benign Ovarian Tumor

Metagenomic Analysis of Serum Microbe-Derived Extracellular Vesicles and Diagnostic Models to Differentiate Ovarian Cancer and Benign Ovarian Tumor

We aimed to develop a diagnostic model identifying ovarian cancer (OC) from benign ovarian tumors using metagenomic data from serum microbe-derived extracellular vesicles (EVs). We obtained serum samples from 166 patients with pathologically confirmed OC and 76 patients with benign ovarian tumors. F...

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Bibliographic Details
Main Authors: Se Ik Kim, Nayeon Kang, Sangseob Leem, Jinho Yang, HyunA Jo, Maria Lee, Hee Seung Kim, Danny N. Dhanasekaran, Yoon-Keun Kim, Taesung Park, Yong Sang Song
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
ovarian neoplasms
ovarian carcinoma
extracellular vesicle
microbiome
metagenomic analysis
diagnostic model
Online Access:https://www.mdpi.com/2072-6694/12/5/1309

Internet

https://www.mdpi.com/2072-6694/12/5/1309

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