Synergistic Effect of the Long-Term Overexpression of Bcl-2 and BDNF Lentiviral in Cell Protecting against Death and Generating TH Positive and CHAT Positive Cells from MSC

Synergistic Effect of the Long-Term Overexpression of Bcl-2 and BDNF Lentiviral in Cell Protecting against Death and Generating TH Positive and CHAT Positive Cells from MSC

Mesenchymal stem cells (MSC) are potentially a good material for transplantation in many diseases, including neurodegenerative diseases. The main problem with using them is the low percentage of surviving cells after the transplant procedure and the naturally poor ability of MSC to spontaneously dif...

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Bibliographic Details
Main Authors: Paulina Borkowska, Aleksandra Zielinska, Monika Paul-Samojedny, Rafał Stojko, Jan Kowalski
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
lentiviral transduction
BDNF
Bcl-2
mesenchymal stem cells
cholinergic neurons
dopaminergic neurons
Online Access:https://www.mdpi.com/1422-0067/22/13/7086

Internet

https://www.mdpi.com/1422-0067/22/13/7086

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