Molecular alterations and targeted therapy in pancreatic ductal adenocarcinoma

Molecular alterations and targeted therapy in pancreatic ductal adenocarcinoma

Abstract Pancreatic ductal adenocarcinoma (PDAC) is a malignancy characterized by a poor prognosis and high mortality rate. Genetic mutations and altered molecular pathways serve as targets in precise therapy. Using next-generation sequencing (NGS), these aberrant alterations can be identified and u...

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Bibliographic Details
Main Authors: Yunzhen Qian, Yitao Gong, Zhiyao Fan, Guopei Luo, Qiuyi Huang, Shengming Deng, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Chen Liu
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Hematology & Oncology
Subjects:
Therapeutic targets
Precision oncology
Pancreatic ductal adenocarcinoma
Oncogenes
Tumour suppressors
Epigenetics
Online Access:http://link.springer.com/article/10.1186/s13045-020-00958-3

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http://link.springer.com/article/10.1186/s13045-020-00958-3

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