Production of Cyclin D1 specific siRNAs by double strand processing for gene therapy of esophageal squamous cell carcinoma

Production of Cyclin D1 specific siRNAs by double strand processing for gene therapy of esophageal squamous cell carcinoma

Background: RNAi (RNA interference) is a new strategy in gene therapy and biotechnology which provides new promises in the treatment of different diseases such as cancer and viral diseases. CCND1 which is a key gene in cell cycle is amplified and over expressed in esophageal cancer. The objective of...

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Bibliographic Details
Main Authors: Negar Mottaghi-Dastjerdi, Mohammad Soltany-Rezaee-Rad, Abolghasem Ajami, Alireza Rafiei, Saeid Abediankenari, Eshrat Gharaee, Mohammad bagher Hashemi Sooteh, Fatemeh Rahbarizadeh
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences and Health Services 2013-02-01
Series:Research in Molecular Medicine
Subjects:
dsRNA digestion
siRNA
RNAi
dsRNA
esophageal cancer
CCND1
Online Access:http://rmm.mazums.ac.ir/browse.php?a_code=A-10-25-2&slc_lang=en&sid=1

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http://rmm.mazums.ac.ir/browse.php?a_code=A-10-25-2&slc_lang=en&sid=1

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