TAK1 Is a Novel Target in Hepatocellular Carcinoma and Contributes to Sorafenib ResistanceSummary

Background & Aims: Identifying novel and actionable targets in hepatocellular carcinoma (HCC) remains an unmet medical need. TAK1 was originally identified as a transforming growth factor-β–activated kinase and was further proved to phosphorylate and activate numerous downstream targets and...

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Bibliographic Details
Main Authors: Shunjie Xia, Lin Ji, Liye Tao, Yu Pan, Zhongjie Lin, Zhe Wan, Haoqi Pan, Jie Zhao, Liuxin Cai, Junjie Xu, Xiujun Cai
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X21000874