Gene Expression and Epigenetic Changes in Mice Following Inhalation of Copper(II) Oxide Nanoparticles

Gene Expression and Epigenetic Changes in Mice Following Inhalation of Copper(II) Oxide Nanoparticles

We investigated the transcriptomic response and epigenetic changes in the lungs of mice exposed to inhalation of copper(II) oxide nanoparticles (CuO NPs) (8 &#215; 10<sup>5</sup> NPs/m<sup>3</sup>) for periods of 3 days, 2 weeks, 6 weeks, and 3 months. A whole genome tran...

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Bibliographic Details
Main Authors: Pavel Rossner, Kristyna Vrbova, Andrea Rossnerova, Tana Zavodna, Alena Milcova, Jiri Klema, Zbynek Vecera, Pavel Mikuska, Pavel Coufalik, Lukas Capka, Kamil Krumal, Bohumil Docekal, Vladimir Holan, Miroslav Machala, Jan Topinka
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Nanomaterials
Subjects:
copper(ii) oxide nanoparticles
inhalation
mouse
gene expression
dna methylation
Online Access:https://www.mdpi.com/2079-4991/10/3/550

Internet

https://www.mdpi.com/2079-4991/10/3/550

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