A young adult patient with Li-Fraumeni syndrome-associated glioblastoma: Case discussion and literature review

A young adult patient with Li-Fraumeni syndrome-associated glioblastoma: Case discussion and literature review

Li-Fraumeni syndrome is an autosomal dominant cancer predisposition syndrome caused by germ line alterations in the tumor suppressor gene TP53, with an incidence of 1 in 5000–1 in 20,000. Li-Fraumeni syndrome is associated with numerous malignancies, including astrocytoma. Here, we report the case o...

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Bibliographic Details
Main Authors: Xiaoyu Wu, Suqing Tian, Biling Liang, Qunying Yang, Hokeung Ng, Shaoxiong Wu, Qing Chang, Zhong-ping Chen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Glioma
Subjects:
glioblastoma
li-fraumeni syndrome
prognosis
temozolomide
tp53 mutation
Online Access:http://www.jglioma.com/article.asp?issn=2589-6113;year=2020;volume=3;issue=2;spage=71;epage=75;aulast=Wu

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http://www.jglioma.com/article.asp?issn=2589-6113;year=2020;volume=3;issue=2;spage=71;epage=75;aulast=Wu

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