Cerebral malaria: gamma-interferon redux

Cerebral malaria: gamma-interferon redux

There are two theories that seek to explain the pathogenesis of cerebral malaria, the mechanical obstruction hypothesis and the immunopathology hypothesis. Evidence consistent with both ideas has accumulated from studies of the human disease and experimental models. Thus some combination of these co...

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Bibliographic Details
Main Authors: Nicholas H Hunt, Helen J Ball, Anna S Hansen, Loke Tim Khaw, Jintao eGuo, Supun eBakmiwewa, Andrew J Mitchell, Valéry eCombes, Georges E.R. Grau
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Blood-Brain Barrier
Interferon-gamma
microparticles
platelets
immunopathology
kynurenine pathway
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00113/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00113/full

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