Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy

Aptamers are a class of small nucleic acid ligands that are composed of RNA or single-stranded DNA oligonucleotides and have high specificity and affinity for their targets. Similar to antibodies, aptamers interact with their targets by recognizing a specific three-dimensional structure and are thus...

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Bibliographic Details
Main Authors: Hongguang Sun, Xun Zhu, Patrick Y Lu, Roberto R Rosato, Wen Tan, Youli Zu
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116303213