RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology

RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology

Accumulation of toxic proteins in neurons has been linked with the onset of neurodegenerative diseases, which in many cases are characterized by altered neuronal function and synapse loss. Molecular chaperones help protein folding and the resolubilization of unfolded proteins, thereby reducing the p...

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Bibliographic Details
Main Authors: Sandeep Raut, Bhagaban Mallik, Arpan Parichha, Valsakumar Amrutha, Chandan Sahi, Vimlesh Kumar
Format: Article
Language:English
Published: Oxford University Press 2017-07-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Drosophila
chaperones
RNAi
eye morphogenesis
neuromuscular junction
Mutant Screen Report
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.041632

Internet

http://g3journal.org/lookup/doi/10.1534/g3.117.041632

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