Inhibition of nuclear factor-kappa B activation decreases survival of Mycobacterium tuberculosis in human macrophages.

Inhibition of nuclear factor-kappa B activation decreases survival of Mycobacterium tuberculosis in human macrophages.

Nuclear factor-kappa B (NFκB) is a ubiquitous transcription factor that mediates pro-inflammatory responses required for host control of many microbial pathogens; on the other hand, NFκB has been implicated in the pathogenesis of other inflammatory and infectious diseases. Mice with genetic disrupti...

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Bibliographic Details
Main Authors: Xiyuan Bai, Nicole E Feldman, Kathryn Chmura, Alida R Ovrutsky, Wen-Lin Su, Laura Griffin, Dohun Pyeon, Mischa T McGibney, Matthew J Strand, Mari Numata, Seiji Murakami, Loretta Gaido, Jennifer R Honda, William H Kinney, Rebecca E Oberley-Deegan, Dennis R Voelker, Diane J Ordway, Edward D Chan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3636238?pdf=render

Internet

http://europepmc.org/articles/PMC3636238?pdf=render

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