Inhibition of nuclear factor-kappa B activation decreases survival of Mycobacterium tuberculosis in human macrophages.
Nuclear factor-kappa B (NFκB) is a ubiquitous transcription factor that mediates pro-inflammatory responses required for host control of many microbial pathogens; on the other hand, NFκB has been implicated in the pathogenesis of other inflammatory and infectious diseases. Mice with genetic disrupti...
Main Authors: | Xiyuan Bai, Nicole E Feldman, Kathryn Chmura, Alida R Ovrutsky, Wen-Lin Su, Laura Griffin, Dohun Pyeon, Mischa T McGibney, Matthew J Strand, Mari Numata, Seiji Murakami, Loretta Gaido, Jennifer R Honda, William H Kinney, Rebecca E Oberley-Deegan, Dennis R Voelker, Diane J Ordway, Edward D Chan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3636238?pdf=render |
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