Repeatable, Inducible Micro-RNA-Based Technology Tightly Controls Liver Transgene Expression

Repeatable, Inducible Micro-RNA-Based Technology Tightly Controls Liver Transgene Expression

Inducible systems for gene expression emerge as a new class of artificial vectors offering temporal and spatial exogenous control of gene expression. However, most inducible systems are less efficient in vivo and lack the target-organ specificity. In the present study, we have developed and optimize...

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Bibliographic Details
Main Authors: Iulian I Oprea, Joana R Viola, Pedro M D Moreno, Oscar E Simonson, Sergey Rodin, Nathalie Teller, Karl Tryggvason, Karin E Lundin, Leonard Girnita, Carl Inge Edvard Smith
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
cell type specific
liver expression
long-term gene expression
reporter system
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116303146

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http://www.sciencedirect.com/science/article/pii/S2162253116303146

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