Liver-specific knockdown of ANGPTL8 alters the structure of the gut microbiota in mice

Liver-specific knockdown of ANGPTL8 alters the structure of the gut microbiota in mice

Abstract Purpose To investigate the effect of liver-specific knockdown of ANGPTL8 on the structure of the gut microbiota. Methods We constructed mice with liver-specific ANGPTL8 knockdown by using an adeno-associated virus serotype 8 (AAV8) system harbouring an ANGPTL8 shRNA. We analysed the structu...

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Bibliographic Details
Main Authors: Yinlong Cheng, Yining Li, Yonghong Xiong, Yixin Zou, Siyu Chen, Wenxiang Zhang, Chang Liu, Yujie Shi
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Annals of Microbiology
Subjects:
ANGPTL8
Gut microbiota
Pyrosequencing
KEGG functional prediction
Online Access:https://doi.org/10.1186/s13213-020-01599-0

Internet

https://doi.org/10.1186/s13213-020-01599-0

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