Interleukin (IL)-1β Is a Strong Inducer of IL-36γ Expression in Human Colonic Myofibroblasts.

Interleukin (IL)-36 cytokines are members of the IL-1 cytokine family. In this study, we investigated the expression of IL-36γ in human colonic myofibroblasts to explore the molecular mechanisms underlying IL-36γ induction.IL-36 mRNA was analyzed by real-time PCR method. Secretion of IL-36γ protein...

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Bibliographic Details
Main Authors: Kenichiro Takahashi, Atsushi Nishida, Makoto Shioya, Hirotsugu Imaeda, Shigeki Bamba, Osamu Inatomi, Tomoharu Shimizu, Katsuyuki Kitoh, Akira Andoh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4643060?pdf=render