Clinical and Pre-Clinical Evidence of Carbonic Anhydrase IX in Pancreatic Cancer and Its High Expression in Pre-Cancerous Lesions

Clinical and Pre-Clinical Evidence of Carbonic Anhydrase IX in Pancreatic Cancer and Its High Expression in Pre-Cancerous Lesions

Hypoxia is a common phenomenon that occurs in most solid tumors. Regardless of tumor origin, the evolution of a hypoxia-adapted phenotype is critical for invasive cancer development. Pancreatic ductal adenocarcinoma is also characterized by hypoxia, desmoplasia, and the presence of necrosis, predict...

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Bibliographic Details
Main Authors: Sabina Strapcova, Martina Takacova, Lucia Csaderova, Paola Martinelli, Lubomira Lukacikova, Viliam Gal, Juraj Kopacek, Eliska Svastova
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
carbonic anhydrase IX
pancreatic cancer
intraductal papillary mucinous neoplasia
acidic microenvironment
hypoxia
correlation analysis
Online Access:https://www.mdpi.com/2072-6694/12/8/2005

Internet

https://www.mdpi.com/2072-6694/12/8/2005

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