miR-10a inhibits cell proliferation and promotes cell apoptosis by targeting BCL6 in diffuse large B-cell lymphoma

miR-10a inhibits cell proliferation and promotes cell apoptosis by targeting BCL6 in diffuse large B-cell lymphoma

Abstract The BCL6 (B-Cell Lymphoma 6) gene is a proto-oncogene that is often expressed in diffuse large B-cell lymphomas (DLBCLs). BCL6 loss of function can kill DLBCL cells, demonstrating that BCL6 is necessary for the survival of DLBCL cells and could be a therapeutic target. In this study, we fou...

Full description

Bibliographic Details
Main Authors: Qian Fan, Xiangrui Meng, Hongwei Liang, Huilai Zhang, Xianming Liu, Lanfang Li, Wei Li, Wu Sun, Haiyang Zhang, Ke Zen, Chen-Yu Zhang, Zhen Zhou, Xi Chen, Yi Ba
Format: Article
Language:English
Published: SpringerOpen 2016-11-01
Series:Protein & Cell
Subjects:
microRNA
miR-10a
BCL6
DLBCL
proliferation
apoptosis
Online Access:http://link.springer.com/article/10.1007/s13238-016-0316-z

Internet

http://link.springer.com/article/10.1007/s13238-016-0316-z

Similar Items