Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?

Exosomes are small membranous vesicles secreted by a number of cell types including neurons and can be isolated from conditioned cell media or bodily fluids such as urine and plasma. Exosome biogenesis involves the inward budding of endosomes to form multivesicular bodies (MVB). When fused with the...

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Bibliographic Details
Main Authors: Shayne Anthony Bellingham, Belinda eGuo, Bradley eColeman, Andrew Francis Hill
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00124/full