CTLA4 variants and haplotype contribute genetic susceptibility to myasthenia gravis in northern Chinese population.

Cytotoxic T lymphocyte-associated antigen-4 (CTLA4), a critical negative regulator of the T-cell response, has been considered a candidate for many autoimmune diseases. Evidence from Caucasians supported a genetic predisposition of CTLA4 to myasthenia gravis (MG), but the contribution in East Asians...

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Bibliographic Details
Main Authors: Liang Sun, Yunxiao Meng, Yanchen Xie, Hua Zhang, Zheng Zhang, Xiaoxia Wang, Bin Jiang, Wei Li, Yao Li, Ze Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4086970?pdf=render