SOCS3 deficiency in leptin receptor-expressing cells mitigates the development of pregnancy-induced metabolic changes

SOCS3 deficiency in leptin receptor-expressing cells mitigates the development of pregnancy-induced metabolic changes

Objective: During pregnancy, women normally increase their food intake and body fat mass, and exhibit insulin resistance. However, an increasing number of women are developing metabolic imbalances during pregnancy, including excessive gestational weight gain and gestational diabetes mellitus. Despit...

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Bibliographic Details
Main Authors: Thais T. Zampieri, Angela M. Ramos-Lobo, Isadora C. Furigo, João A.B. Pedroso, Daniella C. Buonfiglio, Jose Donato Jr.
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Molecular Metabolism
Subjects:
Leptin
Suppressor of cytokine signaling
Gestational diabetes
Obesity
Leptin resistance
Hypothalamus
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877814002063

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http://www.sciencedirect.com/science/article/pii/S2212877814002063

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