Small ncRNA Expression-Profiling of Blood from Hemophilia A Patients Identifies miR-1246 as a Potential Regulator of Factor 8 Gene.

Small ncRNA Expression-Profiling of Blood from Hemophilia A Patients Identifies miR-1246 as a Potential Regulator of Factor 8 Gene.

Hemophilia A (HA) is a bleeding disorder caused by deficiency of functional plasma clotting factor VIII (FVIII). Genetic mutations in the gene encoding FVIII (F8) have been extensively studied. Over a thousand different mutations have been reported in the F8 gene. These span a diverse range of mutat...

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Bibliographic Details
Main Authors: Tewarit Sarachana, Neetu Dahiya, Vijaya L Simhadri, Gouri Shankar Pandey, Surbhi Saini, Christine Guelcher, Michael F Guerrera, Chava Kimchi-Sarfaty, Zuben E Sauna, Chintamani D Atreya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4503767?pdf=render

Internet

http://europepmc.org/articles/PMC4503767?pdf=render

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