High-content imaging assay to evaluate Toxoplasma gondii infection and proliferation: A multiparametric assay to screen new compounds.

Toxoplasma gondii is an intracellular protozoan parasite widely distributed in animals and humans. Infection of host cells and parasite proliferation are essential steps in Toxoplasma pathology. The objective of this study was to develop and validate a novel automatic High Content Imaging (HCI) assa...

Full description

Bibliographic Details
Main Authors: Bastien Touquet, Léonie Pelissier, Pierre Cavailles, Wei Yi, Valeria Bellini, Corinne Mercier, Marie-France Cesbron-Delauw, Ahcène Boumendjel, Delphine Aldebert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6115017?pdf=render