Markers for blood-brain barrier integrity: how appropriate is Evans blue in the 21st century and what are the alternatives?

In recent years there has been a resurgence of interest in brain barriers and various roles their intrinsic mechanisms may play in neurological disorders. Such studies require suitable models and markers to demonstrate integrity and functional changes at the interfaces between blood, brain and cereb...

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Bibliographic Details
Main Authors: Norman Ruthven Saunders, Katarzyna Magdalena Dziegielewska, Kjeld eMøllgård, Mark eHabgood
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00385/full