Host genetic background influences the response to the opportunistic Pseudomonas aeruginosa infection altering cell-mediated immunity and bacterial replication.

Pseudomonas aeruginosa is a common cause of healthcare-associated infections including pneumonia, bloodstream, urinary tract, and surgical site infections. The clinical outcome of P. aeruginosa infections may be extremely variable among individuals at risk and patients affected by cystic fibrosis. H...

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Bibliographic Details
Main Authors: Maura De Simone, Lorenza Spagnuolo, Nicola Ivan Lorè, Giacomo Rossi, Cristina Cigana, Ida De Fino, Fuad A Iraqi, Alessandra Bragonzi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182038?pdf=render