Identification of slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour

Identification of slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour

To facilitate smoking genetics research we determined whether a screen of mutagenized zebrafish for nicotine preference could predict loci affecting smoking behaviour. From 30 screened F3 sibling groups, where each was derived from an individual ethyl-nitrosurea mutagenized F0 fish, two showed incre...

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Bibliographic Details
Main Authors: Judit García-González, Alistair J Brock, Matthew O Parker, Riva J Riley, David Joliffe, Ari Sudwarts, Muy-Teck Teh, Elisabeth M Busch-Nentwich, Derek L Stemple, Adrian R Martineau, Jaakko Kaprio, Teemu Palviainen, Valerie Kuan, Robert T Walton, Caroline H Brennan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-03-01
Series:eLife
Subjects:
slit3
acoustic startle
smoking
conditioned place preference
gene association
nicotine
Online Access:https://elifesciences.org/articles/51295

Internet

https://elifesciences.org/articles/51295

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