Methods for Detection of Matrix Metalloproteinases as Biomarkers in Cardiovascular Disease

Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteolytic enzymes that degrade extracellular matrix (ECM) components like collagen, fibronectin, and laminin. While this activity is important for normal development, morphogenesis, and wound healing, deregulation of MMP activity has...

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Bibliographic Details
Main Authors: Viorica Lopez-Avila, Juliet V. Spencer
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Clinical Medicine Insights: Cardiology
Online Access:https://doi.org/10.4137/CMC.S484