Prognostic Value of Serum Caspase-Cleaved Cytokeratin-18 Levels before Liver Transplantation for One-Year Survival of Patients with Hepatocellular Carcinoma

Prognostic Value of Serum Caspase-Cleaved Cytokeratin-18 Levels before Liver Transplantation for One-Year Survival of Patients with Hepatocellular Carcinoma

Cytokeratin (CK)-18 is the major intermediate filament protein in the liver and during hepatocyte apoptosis is cleaved by the action of caspases; the resulting fragments are released into the blood as caspase-cleaved cytokeratin (CCCK)-18. Higher circulating levels of CCCK-18 have been found in pati...

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Bibliographic Details
Main Authors: Leonardo Lorente, Sergio T. Rodriguez, Pablo Sanz, Antonia Pérez-Cejas, Javier Padilla, Dácil Díaz, Antonio González, María M. Martín, Alejandro Jiménez, Manuel A. Barrera
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:International Journal of Molecular Sciences
Subjects:
cytokeratin
hepatocellular carcinoma
liver transplantation
mortality
outcome
Online Access:http://www.mdpi.com/1422-0067/17/9/1524

Internet

http://www.mdpi.com/1422-0067/17/9/1524

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