pulver: an R package for parallel ultra-rapid p-value computation for linear regression interaction terms

pulver: an R package for parallel ultra-rapid p-value computation for linear regression interaction terms

Abstract Background Genome-wide association studies allow us to understand the genetics of complex diseases. Human metabolism provides information about the disease-causing mechanisms, so it is usual to investigate the associations between genetic variants and metabolite levels. However, only consid...

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Bibliographic Details
Main Authors: Sophie Molnos, Clemens Baumbach, Simone Wahl, Martina Müller-Nurasyid, Konstantin Strauch, Rui Wang-Sattler, Melanie Waldenberger, Thomas Meitinger, Jerzy Adamski, Gabi Kastenmüller, Karsten Suhre, Annette Peters, Harald Grallert, Fabian J. Theis, Christian Gieger
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Bioinformatics
Subjects:
Algorithm
Linear regression interaction term
SNP–CpG interaction
Software
Online Access:http://link.springer.com/article/10.1186/s12859-017-1838-y

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http://link.springer.com/article/10.1186/s12859-017-1838-y

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