Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51.

Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51.

BACKGROUND:Pfs25 and Pvs25, surface proteins of mosquito stage of the malaria parasites P. falciparum and P. vivax, respectively, are leading candidates for vaccines preventing malaria transmission by mosquitoes. This single blinded, dose escalating, controlled Phase 1 study assessed the safety and...

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Bibliographic Details
Main Authors: Yimin Wu, Ruth D Ellis, Donna Shaffer, Erica Fontes, Elissa M Malkin, Siddhartha Mahanty, Michael P Fay, David Narum, Kelly Rausch, Aaron P Miles, Joan Aebig, Andrew Orcutt, Olga Muratova, Guanhong Song, Lynn Lambert, Daming Zhu, Kazutoyo Miura, Carole Long, Allan Saul, Louis H Miller, Anna P Durbin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18612426/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18612426/?tool=EBI

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