The model of circulating immune complexes and interleukin-6 improves the prediction of disease activity in systemic lupus erythematosus

Abstract Systemic Lupus Erythematosus (SLE) is an autoimmune disease resulting in autoantibody production, immune complex deposition, and complement activation. The standard biomarkers such as anti-dsDNA and complements (C3 and C4) do not always correlate with active clinical SLE. The heterogeneity...

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Bibliographic Details
Main Authors: Chokchai Thanadetsuntorn, Pintip Ngamjanyaporn, Chavachol Setthaudom, Kenneth Hodge, Nisara Saengpiya, Prapaporn Pisitkun
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-20947-4