High-dose methotrexate in ICU patients: a retrospective study

High-dose methotrexate in ICU patients: a retrospective study

Abstract Background High-dose methotrexate (HD-MTX) is commonly used in the treatment of solid tumors and hematological malignancies. Severe toxicities are frequent, leading to organ dysfunction and death. Risk–benefit ratio of using HD-MTX in critically ill patients is unknown. This study aims to d...

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Bibliographic Details
Main Authors: Sandrine Valade, Eric Mariotte, Elie Azoulay, Michael Darmon
Format: Article
Language:English
Published: SpringerOpen 2020-06-01
Series:Annals of Intensive Care
Subjects:
Methotrexate
Acute kidney injury
Outcome
Hematological malignancies
Drug-related side effects
Antineoplastic agents
Online Access:http://link.springer.com/article/10.1186/s13613-020-00693-5

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http://link.springer.com/article/10.1186/s13613-020-00693-5

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