HPA axis gene expression and DNA methylation profiles in rats exposed to early life stress, adult voluntary ethanol drinking and single housing

HPA axis gene expression and DNA methylation profiles in rats exposed to early life stress, adult voluntary ethanol drinking and single housing

The neurobiological basis of early life stress (ELS) impact on vulnerability to alcohol use disorder is not fully understood. The effect of ELS, adult ethanol consumption and single housing, on expression of stress and DNA methylation regulatory genes as well as blood corticosterone levels was inves...

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Bibliographic Details
Main Authors: Aniruddha eTodkar, Linnea eGranholm, Mujtaba eAljumah, Kent W Nilsson, Erika eComasco, Ingrid eNylander
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
DNA Methylation
Ethanol
Gene Expression
Housing
Hypothalamus
Pituitary Gland
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00090/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00090/full

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