Progranulin promotes osteogenic differentiation of periodontal membrane stem cells in both inflammatory and non-inflammatory conditions

Objective The growth factor progranulin (PGRN) is widely expressed and plays important roles in anti-inflammatory signaling and bone regeneration. However, the anti-inflammatory and pro-osteogenic roles of PGRN in periodontitis are seldom studied. We used an in vitro model to investigate whether PGR...

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Bibliographic Details
Main Authors: Miao Yu, Long Sun, Pengfei Ba, Linxia Li, Jing Chen, Qinfeng Sun
Format: Article
Language:English
Published: SAGE Publishing 2021-08-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605211032508